Stable kinetochore-microtubule attachment requires loop-dependent Ndc80-Ndc80 binding
S. Polley, H. Müschenborn, M. Terbeck, A. De Antoni, I. R. Vetter, M. Dogterom, A. Musacchio, V. A. Volkov, P. J. Huis in 't Veld
This study shows that the Ndc80 loop facilitates Ndc80-Ndc80 interactions, which are essential for stable kinetochore-microtubule attachments and proper chromosome congression.
bioRxiv · Aug 25, 2022Biochemistry