Efficient inhibition of cell proliferation and promotion of apoptosis requires continuous treatment with abemaciclib.
R. Torres-Guzman, M. P. Ganado, C. Mur, C. Marugan, C. Baquero, Y. Yang, Y. Zeng, H. Bian, J. Du, A. de Dios, O. Puig, M. J. Lallena
This study shows abemaciclib, a CDK4/6 inhibitor, effectively inhibits cell proliferation and induces apoptosis with continuous treatment, outperforming other CDK4/6 inhibitors in breast cancer cell lines.
bioRxiv · Nov 15, 2021 · PreprintCell Biology