Dual genome-wide CRISPR knockout and CRISPR activation screens identify common mechanisms that regulate the resistance to multiple ATR inhibitors
E. M. Schleicher, A. Dhoonmoon, K. E. Clements, L. M. Jackson, C. L. Stump, C. M. Nicolae, G.-L. Moldovan
The paper uses dual CRISPR screens to identify genes affecting resistance to ATR inhibitors in cancer cells.
bioRxiv · Apr 8, 2020Cancer Biology