KD-64 - a new selective A2A adenosine receptor antagonist has anti-inflammatory activity but contrary to the non-selective antagonist - caffeine does not reduce diet-induced obesity in mice
M. Kotanska, A. Dziubina, M. Szafarz, K. Mika, K. Reguła, M. Bednarski, M. Zygmunt, A. Drabczynska, J. Sapa, K. Kiec-Kononowicz
KD-64, a selective A2A adenosine receptor antagonist, shows anti-inflammatory effects and improves glucose tolerance in obese mice, unlike caffeine which does not reduce obesity but increases inflammation markers.
bioRxiv · Feb 17, 2020Pharmacology & Toxicology