Nonlinear mechanics of lamin filaments and the meshwork topology build an emergent nuclear lamina
T. Sapra, Z. Qin, M. J. Buehler, U. Aebi, A. Dubrowsky-Gaupp, D. J. Mueller, O. Medalia
The paper measures the mechanical properties of lamin filaments in their native meshwork using multiple techniques and finds they exhibit non-Hookean behavior and small-world network topology.
bioRxiv · Nov 18, 2019Biophysics