A High Avidity Biosensor Reveals PI(3,4)P2 is Predominantly a Class I PI3K Signaling Product
B. Goulden, J. Pacheco, A. Dull, J. Zewe, A. Deiters, G. R. Hammond
The paper develops a high-avidity biosensor for PI(3,4)P2, revealing it is mainly produced by class I PI3K and hydrolyzed by PTEN.
bioRxiv · Sep 6, 2018Cell Biology