Phosphatidylinositol 3-kinase-independent synthesis of PtdIns(3,4)P2 by a phosphotransferase
G. Walpole, J. Pacheco, N. Chauhan, Y. Abbas, F. Montano-Rendon, Z. Liu, H. Zhu, J. H. Brumell, A. Deiters, G. R. Hammond, S. Grinstein, G. D. Fairn
The paper shows that Salmonella and Shigella effectors generate PtdIns(3,4)P2 independently of phosphoinositide 3-kinases using a phosphotransferase mechanism.
bioRxiv · May 25, 2021 · PreprintCell Biology