Author

A. Dupont

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Biophysics· 1 Cell Biology· 1 Ecology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1

Frequent Co-Authors

A. Coullomb· 1 shared A. H. Lombard· 1 shared C. Holland· 1 shared C. M. Bidan· 1 shared C. Nidercorne· 1 shared C. W. Heegaard· 1 shared D. Jegou· 1 shared D. Wustner· 1 shared

Activity by Year

2017-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 7 mutual co-author links

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1 shared paperBiophysics

A. Coullomb

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

A social-ecological geography of southern Canadian Lakes

A. Dupont, M. Botrel, N. Fortin St-Gelais, T. Poisot, R. Maranger

The paper develops a social-ecological framework to assess lake health and vulnerability across southern Canadian lakes, identifying key indicators of ecological alteration and recreational use.

bioRxiv · Mar 9, 2023Ecology

IL4I1 binds to TMPRSS13 and competes with SARS-Cov2 Spike

J. Gatineau, C. Nidercorne, A. Dupont, M.-L. Puiffe, J. L. Cohen, V. Molinier-Frenkel, F. Niedergang, F. Castellano

The paper identifies IL4I1's interaction with TMPRSS13 and shows it competes with SARS-CoV-2 Spike for binding, inhibiting viral entry and immunosuppression.

bioRxiv · Dec 23, 2021 · PreprintImmunology

Conditional deletion of HIF-1α provides new insight regarding the murine response to gastrointestinal infection with Salmonella Typhimurium

L. Robrahn, A. Dupont, S. Jumpertz, K. Zhang, C. Holland, J. Guillaume, S. Rappold, V. Cerovic, J. Saez, M. Hornef, T. Cramer

This study investigates the role of HIF-1α in murine responses to Salmonella Typhimurium infection using conditional deletion, finding it dispensable or compensable in immune defense.

bioRxiv · Jan 16, 2021 · PreprintMicrobiology

Molecular and functional diversity of distinct subpopulations of extracellular vesicles from stressed pancreatic beta cells: implications for autoimmunity

K. R. Giri, L. De Beaurepaire, D. Jegou, M. Lavy, M. Mosser, A. Dupont, R. Fleurisson, L. Dubreil, M. Collot, P. Van Endert, J.-M. Bach, G. Mignot, S. Bosch

This study compares extracellular vesicles from stressed pancreatic beta cells and finds that inflammation increases vesiculome volume and immune-stimulatory material release, with differential sorting of cytokines and microRNAs into subpopulations.

bioRxiv · Mar 26, 2020 · PreprintImmunology

Analysis of cholesterol export from endo-lysosomes by Niemann Pick C2 protein using combined fluorescence and X-ray microscopy

A. Dupont, F. Lund, M. L. V. Jensen, M. Szomek, G. K. Nielsen, C. W. Heegaard, P. Guttmann, S. Werner, J. McNally, G. Schneider, S. Kapishnikov, D. Wustner

This study uses fluorescence and X-ray microscopy to show NPC2 facilitates cholesterol export from endo-lysosomes, altering membrane trafficking and organelle structure.

bioRxiv · Nov 6, 2018 · PreprintCell Biology

Magneto-active substrates for local mechanical stimulation of living cells

C. M. Bidan, M. Fratzl, A. Coullomb, P. Moreau, A. H. Lombard, I. Wang, M. Balland, T. Boudou, N. M. Dempsey, T. Devillers, A. Dupont

The paper develops magneto-active substrates to apply local and dynamic mechanical stimulation to single cells, enabling study of mechanotransduction through traction and compression.

bioRxiv · Oct 17, 2017Biophysics