C. Holland

Silk Road Revealed: Mechanism of silk fibre formation in Bombyx mori

This study redefines the molecular structure of fibroin heavy chain and its role in the transition from solution to fibre.

The timid invasion: Behavioral adjustments favor range expansion in a non-native rodent

The paper examines behavioral differences between invasive voles and native mice, finding that voles at invasion edges show more cautious and flexible behaviors, potentially aiding their range expansion.

In situ identification of secondary structures in unpurified Bombyx mori silk fibrils using polarized two-dimensional infrared spectroscopy

This study uses polarized 2D infrared spectroscopy to identify secondary structures in Bombyx mori silk fibrils without peak fitting, showing hydration affects random-coil and -helix content but not beta-sheet content.

Species-typical chemical signals mediate reproductive isolation in a teleost fish

The authors withdrew their manuscript due to invalid behavioral data with duplicated values, rendering analyses and conclusions unreliable.

Conditional deletion of HIF-1α provides new insight regarding the murine response to gastrointestinal infection with Salmonella Typhimurium

This study investigates the role of HIF-1α in murine responses to Salmonella Typhimurium infection using conditional deletion, finding it dispensable or compensable in immune defense.

A functional landscape of chronic kidney disease entities from public transcriptomic data

This paper integrates transcriptomic data from nine CKD entities to delineate their molecular differences and identify potential therapeutic targets.

Natural selection interacts with the local recombination rate to shape the evolution of hybrid genomes

The persistence of hybrid ancestry is predictable from local recombination rates in three replicate hybrid populations and in humans.

Repeated losses of PRDM9-directed recombination despite the conservation of PRDM9 across vertebrates

The paper identifies PRDM9 orthologs across 225 vertebrate species and finds repeated losses of PRDM9-directed recombination despite its conservation, linking complete orthologs to rapid evolution of binding affinity.