Major Histocompatibility Complex class I heavy chains localize in both cytoplasmic and nuclear compartment
M. Gomez-Herranz, A. Dziadosz, S. Mikac, M. Rychlowski, R. Fahraeus, N. Marek-Trzonkowska, E. Chrusciel, Z. Urban-Wojciuk, I. Papak, L. Arcimowicz, T. Marjanski, W. Rzyman, A. Sznarkowska
The paper shows that a fraction of human MHC-I molecules localizes in the nucleus near histone H2B, suggesting potential nuclear antigen loading.
bioRxiv · Sep 13, 2022 · PreprintImmunology