Author

A. E. Cullen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Physiology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 5 Approach:experimental assay· 5 Research Focus:differential expression· 4 Assay:bulk RNA-seq· 3 Organism:human· 3 Organism:mouse· 3 Assay:ChIP-seq· 2 Research Focus:chromatin & epigenetic regulation· 2

Frequent Co-Authors

A. N. Holding· 3 shared F. Markowetz· 3 shared A. M. Centner· 2 shared F. M. Giorgi· 2 shared G. Salazar· 2 shared R. Deitado· 2 shared V. Ukhanov· 2 shared A. Donnelly· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersCancer Biology

A. N. Holding

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Deletion of Robo4 worsens neuroinflammation and motor coordination in a mouse model of Alzheimer's disease

A. E. Cullen, N. Winder, B. Lee, S. Krishna Kumaran, N. Arora, J. Wolf, R. Woltjer, A. Walker

This study shows that Robo4 deletion increases neuroinflammation and impairs motor coordination in Alzheimer's disease mice, with effects dependent on AD mutations and brain region.

bioRxiv · Mar 7, 2024 · PreprintPhysiology

The Role of Sex in the Effects of Smoking and Nicotine in Cardiovascular Function, Atherosclerosis, and Inflammation

G. Salazar, A. M. Centner, A. E. Cullen, L. Khalili, V. Ukhanov, S. Hill, R. Deitado, H. S. Hwang, T. Azeez, J. D. La Favor, O. Laitano, M. S. Parvatiyar

This study investigates sex-specific effects of cigarette smoke and nicotine on cardiovascular function, atherosclerosis, and inflammation in mice, finding sex differences in lipid profiles, plaque composition, and inflammatory markers.

bioRxiv · Feb 13, 2024Cell Biology

The Duality of Adiponectin and the Role of Sex in Atherosclerosis

A. E. Cullen, A. M. Centner, R. Deitado, V. Ukhanov, A. Ismaeel, P. Koutakis, J. Muller-Delp, G. Salazar

This study investigates how adiponectin deficiency affects atherosclerosis differently in males and females, revealing sex- and age-dependent changes in plaque content, inflammation, and vascular smooth muscle cell behavior.

bioRxiv · May 23, 2023Physiology

In Breast Cancer ZMIZ1 Co-Regulates E2F2 as Part of the Estrogen Receptor-Mediated Cell-Cycle Response

W. Zhao, S. F. Rose, R. Blake, A. Godicelj, A. E. Cullen, J. Stenning, L. Beevors, M. Gehrung, S. Kumar, K. Kishore, A. Sawle, M. Eldridge, F. M. Giorgi, K. S. Bridge, F. Markowetz, A. N. Holding

This study identifies ZMIZ1 as a co-regulator of E2F2 in the estrogen receptor-mediated cell-cycle response in breast cancer, showing its role in tumor proliferation and patient prognosis.

bioRxiv · Jan 17, 2023Cancer Biology

VULCAN integrates ChIP-seq with patient-derived co expression networks to identify GRHL2 as a key co-regulator of ERa at enhancers in breast cancer

A. N. Holding, F. M. Giorgi, A. Donnelly, A. E. Cullen, S. Nagarajan, L. A. Selth, F. Markowetz

bioRxiv · Apr 21, 2019Cancer Biology

Genome-wide Estrogen Receptor-alpha activation is sustained, not cyclical

A. N. Holding, A. E. Cullen, F. Markowetz

This study shows that estrogen receptor-alpha binding is sustained, not cyclical, using genome-wide analysis with multiple replicates and a new method.

bioRxiv · Aug 23, 2018Cancer Biology