Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
12 papers
Recent·Most cited
Z. Lyu, X. Lyu, G. Xia, D. Carney, V. M. Alves, M. Falk, N. Arora, H. Zou, A. McGrath, Y. Kang
This study presents structural insights into PAR1 and PAR2 activation by endogenous ligands, revealing a novel mechanism and potential targets for therapeutic development.
bioRxiv · Jul 8, 2024 · PreprintBiochemistry
N. Arora, H. Liang, W. Kattan, W. Yao, H. Ying, J. Liu, Y. Zhou
This study shows that KRAS G12C and G12D mutants respond differently to lipid acyl chain remodeling, affecting their nanoclustering and signaling activities.
bioRxiv · May 30, 2024Cancer Biology
A. E. Cullen, N. Winder, B. Lee, S. Krishna Kumaran, N. Arora, J. Wolf, R. Woltjer, A. Walker
This study shows that Robo4 deletion increases neuroinflammation and impairs motor coordination in Alzheimer's disease mice, with effects dependent on AD mutations and brain region.
bioRxiv · Mar 7, 2024 · PreprintPhysiology
R. Asiimwe, B. Knott, M. E. Greene, E. Wright, M. Bell, D. Epstein, S. D. Yates, M. V. Gonzalez, S. Fry, E. Boydston, S. Clevenger, J. E. Locke, B. E. Brocato, C. M. Burgan, R. Burney, , P. M. Porrett
The paper identifies NFAT inhibition as a cause of reduced uterine natural killer (uNK) cells and pregnancy complications in humans through analysis of uterus transplant recipients.
bioRxiv · Mar 7, 2024 · PreprintImmunology
G. b. Manoharan, C. L. Steffen, K. Pavic, A. Yeste-Vazquez, M. Knuuttila, N. Arora, Y. Zhou, H. Harma, A. Gaigneaux, T. N. Grossmann, D. K. Abankwa
The paper identifies a peptide that disrupts the interaction between Gal1 and B-Raf-RBD, reducing H-Ras nanoclustering and MAPK signaling in cancer cells.
bioRxiv · Sep 7, 2023 · PreprintBiochemistry
M. Pla-Diaz, G. Akguel, M. Molak, L. du Plessis, H. Panagiotopoulou, K. Doan, W. Bogdanowicz, P. Dabrowski, M. Oziemblowski, B. Kwiatkowska, J. Szczurowski, J. Grzelak, N. Arora, K. Majander, F. Gonzalez-Candelas, V. Schuenemann
This study evaluates the impact of reference genome choice on phylogenetic analysis of Treponema pallidum using a novel multiple-reference mapping strategy and ancient genomes.
bioRxiv · Feb 8, 2023 · PreprintMicrobiology
N. Arora, J. P. Hazra, S. Roy, G. K. Bhati, S. Gupta, A. Chaudhuri, A. Sagar, S. RAKSHIT
The paper investigates the mechanical behavior of tip-links in hearing, showing they act as low-force pass filters through slip-ideal-slip bond dynamics and their role in gating-springs.
bioRxiv · Aug 10, 2022 · PreprintBiophysics
V. K. Bajpai, T. Swigut, J. Mohammed, J. Tycko, S. Naqvi, M. Arreola, T. Kim, N. Arora, J. K. Pritchard, M. C. Bassik, J. Wyscoka
A genome-wide CRISPR-Cas9 screen identifies novel genes regulating melanogenesis, many upregulated in dark skin melanocytes and associated with skin color variation.
bioRxiv · Sep 29, 2021 · PreprintCell Biology
J. P. Hazra, A. Sagar, N. Arora, D. Deb, S. P. Kaur, S. Rakshit
The paper investigates how mutations in tip-link proteins disrupt force transmission in inner ear sensors, leading to hearing loss, and shows that Ca2+ can restore function in mutants.
bioRxiv · Apr 19, 2019Biophysics
C. M. McMillen, N. Arora, D. A. Boyles, J. R. Albe, M. R. Kujawa, J. F. Bonadio, C. B. Coyne, A. L. Hartman
This study shows RVFV causes fetal demise by directly infecting the placenta in pregnant rats and humans, revealing vertical transmission in non-livestock species.
bioRxiv · Aug 2, 2018Microbiology