Author

F. M. Giorgi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Plant Biology· 2 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 4 Organism:human· 4 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Approach:statistical model· 3 Organism:Arabidopsis· 2 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:differential expression· 2

Frequent Co-Authors

A. E. Cullen· 2 shared A. N. Holding· 2 shared D. Mercatelli· 2 shared F. Markowetz· 2 shared A. Donnelly· 1 shared A. Godicelj· 1 shared A. Rakhimov· 1 shared A. Sawle· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersCancer Biology

A. E. Cullen

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Author profile →

6 papers

Recent·Most cited

Direct and indirect responses of the Arabidopsis transcriptome to an induced increase in trehalose 6-phosphate

O. Avidan, M. C. M. Martins, R. Feil, M. Lohse, F. M. Giorgi, A. Schlereth, J. E. Lunn, M. Stitt

An induced increase in trehalose 6-phosphate levels affects gene expression directly by inhibiting SnRK1 and indirectly through changes in sucrose levels, impacting growth, metabolism, and signaling pathways.

bioRxiv · Sep 18, 2023Plant Biology

In Breast Cancer ZMIZ1 Co-Regulates E2F2 as Part of the Estrogen Receptor-Mediated Cell-Cycle Response

W. Zhao, S. F. Rose, R. Blake, A. Godicelj, A. E. Cullen, J. Stenning, L. Beevors, M. Gehrung, S. Kumar, K. Kishore, A. Sawle, M. Eldridge, F. M. Giorgi, K. S. Bridge, F. Markowetz, A. N. Holding

This study identifies ZMIZ1 as a co-regulator of E2F2 in the estrogen receptor-mediated cell-cycle response in breast cancer, showing its role in tumor proliferation and patient prognosis.

bioRxiv · Jan 17, 2023Cancer Biology

Copper chelation inhibits TGF-β pathways and suppresses epithelial-mesenchymal transition in cancer

E. M. Poursani, D. Mercatelli, P. Raninga, J. L. Bell, F. Saletta, F. V. Kohane, Y. Zheng, J. Rouaen, T. R. Jue, F. T. Michniewicz, E. Kasiou, M. Tsoli, G. Cirillo, S. Waters, T. Shai-Hee, , O. VITTORIO

This paper shows copper chelation inhibits TGF-β pathways and reduces EMT in cancer cells, potentially offering a new therapeutic strategy for targeting TGF-β in cancer.

bioRxiv · Oct 3, 2022 · PreprintCancer Biology

Preliminary report on SARS-CoV-2 Spike mutation T478K

S. Di Giacomo, D. Mercatelli, A. Rakhimov, F. M. Giorgi

The paper identifies a novel SARS-CoV-2 Spike mutation T478K in over 11,000 cases, predominantly in Mexico and USA, and tracks its emergence since January 2021.

bioRxiv · Mar 28, 2021Evolutionary Biology

Differential submergence tolerance between juvenile and adult Arabidopsis plants involves the ANAC017 transcription factor

L. T. Bui, V. Shukla, F. M. Giorgi, A. Trivellini, P. Perata, F. Licausi, B. Giuntoli

This study identifies ANAC017 as a transcription factor that modulates submergence tolerance in Arabidopsis by integrating stress responses with developmental programs through epigenetic regulation.

bioRxiv · Feb 12, 2020Plant Biology

VULCAN integrates ChIP-seq with patient-derived co expression networks to identify GRHL2 as a key co-regulator of ERa at enhancers in breast cancer

A. N. Holding, F. M. Giorgi, A. Donnelly, A. E. Cullen, S. Nagarajan, L. A. Selth, F. Markowetz

bioRxiv · Apr 21, 2019Cancer Biology