Author

A. E. Downie

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 2 Ecology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:host-pathogen & immune response· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Assay:metagenomics· 1 Organism:multiple species· 1

Frequent Co-Authors

A. L. Graham· 2 shared A. Menezes· 2 shared K. Cadwell· 2 shared O. Mondragon-Palomino· 2 shared P. Loke· 2 shared R. S. Barre· 2 shared A. L. B. Graham· 1 shared A. Mayer· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

A. L. Graham

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Genetic and Environmental interactions contribute to immune variation in rewilded mice

O. O. Oyesola, A. E. Downie, N. Howard, R. S. Barre, K. N. Kiwanuka, Y.-H. Chen, A. Menezes, S. C. Lee, C. Devlin, O. Mondragon-Palomino, C. O. Silva Souza, C. Herrmann, S. B. Koralov, K. Cadwell, A. L. B. Graham, P. Loke

This study examines how genetics and environment interact to influence immune variation in rewilded mice, finding that genotype drives cytokine responses while genotype-environment interactions shape cellular composition.

bioRxiv · Mar 17, 2023Immunology

Social association predicts immunological similarity in rewilded mice

A. E. Downie, O. Oyesola, R. S. Barre, Q. Caudron, Y.- H. Chen, E. J. Dennis, R. Garnier, K. Kiwanuka, A. Menezes, D. J. Navarrete, O. Mondragon-Palomino, J. B. Saunders, C. K. Tokita, K. Zaldana, K. Cadwell, , A. L. Graham

The paper shows that social association in rewilded mice predicts immunological similarity, with social ties more influential than genetic or parasitic factors.

bioRxiv · Mar 15, 2023 · PreprintImmunology

Optimal immune specificity at the intersection of host life history and parasite epidemiology

A. E. Downie, A. Mayer, C. J. E. Metcalf, A. L. Graham

This study examines how life history and epidemiology interact to shape optimal immune strategy using a demographic model of parasite recognition and response.

bioRxiv · Mar 11, 2021Ecology