Author

N. Howard

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

P. Loke· 3 shared O. O. Oyesola· 2 shared A. E. Downie· 1 shared A. L. B. Graham· 1 shared A. Menezes· 1 shared A. Sher· 1 shared B. A. P. Lafont· 1 shared C. Devlin· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersImmunology

P. Loke

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Genetic and Environmental interactions contribute to immune variation in rewilded mice

O. O. Oyesola, A. E. Downie, N. Howard, R. S. Barre, K. N. Kiwanuka, Y.-H. Chen, A. Menezes, S. C. Lee, C. Devlin, O. Mondragon-Palomino, C. O. Silva Souza, C. Herrmann, S. B. Koralov, K. Cadwell, A. L. B. Graham, P. Loke

This study examines how genetics and environment interact to influence immune variation in rewilded mice, finding that genotype drives cytokine responses while genotype-environment interactions shape cellular composition.

bioRxiv · Mar 17, 2023Immunology

Single-cell analysis of CX3CR1+ cells reveal a pathogenic role for BIRC5+ myeloid proliferating cells driven by Staphylococcus aureus leukotoxins

D. G. Loredan, J. C. Devlin, K. A. Lacey, N. Howard, Z. Chen, E. E. Zwack, J.-D. Lin, K. V. Ruggles, K. M. Khanna, V. J. Torres, P. Loke

The paper identifies BIRC5+ myeloid cells as pathogenic during S. aureus infection using scRNA-seq and genetic fate mapping.

bioRxiv · Feb 27, 2023 · PreprintImmunology

Helminth exposure protects against murine SARS-CoV-2 infection through macrophage dependent T cell activation

K. L. Hilligan, O. O. Oyesola, S. Namasivayam, N. Howard, C. S. Clancy, S. D. Oland, N. L. Garza, B. A. P. Lafont, R. F. Johnson, K. D. Mayer-Barber, A. Sher, P. Loke

This study shows that prior helminth infection reduces SARS-CoV-2 viral loads in mice by enhancing CD8+ T cell responses through macrophage-dependent mechanisms.

bioRxiv · Nov 9, 2022 · PreprintImmunology