Author

A. E. Frick-Cheng

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Organism:E. coli· 3 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:gene regulatory network inference· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

H. L. T. Mobley· 4 shared S. N. Smith· 4 shared A. Shea· 2 shared A. Sintsova· 2 shared A. Pirani· 1 shared E. S. Snitkin· 1 shared J. R. Roberts· 1 shared K. A. Eaton· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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4 shared papersMicrobiology

H. L. T. Mobley

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4 papers

Recent·Most cited

Altered motility in response to iron-limitation is regulated by lpdA in uropathogenic E. coli CFT073

A. E. Frick-Cheng, A. Shea, J. R. Roberts, S. N. Smith, M. Ohi, H. L. T. Mobley

This study shows that lpdA regulates iron-mediated motility in UPEC, which impacts virulence under iron-limited conditions.

bioRxiv · Sep 27, 2023 · PreprintMicrobiology

Phenotypic Assessment of Clinical Escherichia coli Isolates Predicts Uropathogenic Potential

A. Shea, A. E. Frick-Cheng, S. N. Smith, H. L. T. Mobley

This study uses phenotypic assays to predict uropathogenic potential of Escherichia coli isolates from UTI cases, showing that certain phenotypes correlate with infection severity.

bioRxiv · Aug 31, 2022Microbiology

Ferric Citrate Uptake is a Virulence Factor in Uropathogenic Escherichia coli

A. E. Frick-Cheng, A. Sintsova, S. N. Smith, A. Pirani, E. S. Snitkin, H. L. T. Mobley

This study identifies the ferric citrate uptake system as a virulence factor in UPEC, showing its role in iron acquisition during UTI and its importance for bacterial fitness.

bioRxiv · Nov 12, 2021Microbiology

The Gene Expression Profile of Uropathogenic Escherichia coli in Women with Uncomplicated Urinary Tract Infections Is Recapitulated in the Mouse Model

A. E. Frick-Cheng, A. Sintsova, S. N. Smith, M. Krauthammer, K. A. Eaton, H. L. T. Mobley

This study compares gene expression of UPEC in human UTIs and a mouse model, finding strong correlation and validating the mouse model's utility for UTI research.

mBio · Aug 25, 2020Peer-reviewedMicrobiology