Author

A. E. Kane

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:machine learning (classical)· 2 Organism:mouse· 2 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:metagenomics· 1

Frequent Co-Authors

D. A. Sinclair· 2 shared J. R. Mitchell· 2 shared M. R. MacArthur· 2 shared S. J. Mitchell· 2 shared E. M. Venable· 1 shared E. Warner· 1 shared F. Grodstein· 1 shared K. S. Chadaideh· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersMicrobiology

D. A. Sinclair

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2 papers

Recent·Most cited

Gut Microbiota predicts Healthy Late-life Aging in Male Mice

S. Ke, S. J. Mitchell, M. R. MacArthur, A. E. Kane, D. A. Sinclair, E. M. Venable, K. S. Chadaideh, R. N. Carmody, F. Grodstein, J. R. Mitchell, Y.-Y. Liu

This study shows that gut microbiota signatures from young mice can predict healthy aging in older mice under calorie restriction.

bioRxiv · Jun 22, 2021Microbiology

Age and life expectancy clocks based on machine learning analysis of mouse frailty

M. B. Schultz, A. E. Kane, S. J. Mitchell, M. R. MacArthur, E. Warner, J. R. Mitchell, S. E. Howlett, M. S. Bonkowski, D. A. Sinclair

This paper develops two machine learning clocks to predict chronological age and life expectancy in mice using Frailty Indices, showing their accuracy in predicting lifespan and intervention efficacy.

bioRxiv · Dec 20, 2019Physiology