Antibiotic-induced accumulation of lipid II sensitizes bacteria to antimicrobial fatty acids
A. E. Sidders, K. M. Kedziora, J. E. Beam, D. Bui, J. B. Parsons, S. E. Rowe, B. P. Conlon
This study shows that combining vancomycin with unsaturated fatty acids enhances killing of S. aureus by promoting lipid II accumulation and membrane disruption.
bioRxiv · May 3, 2022Microbiology