Author

J. E. Beam

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Assay:proteomics· 1

Frequent Co-Authors

S. E. Rowe· 3 shared B. P. Conlon· 2 shared N. J. Wagner· 2 shared A. E. Sidders· 1 shared B. Conlon· 1 shared D. Bui· 1 shared E. S. M. Bahnson· 1 shared J. B. Parsons· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersMicrobiology

S. E. Rowe

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Antibiotic-induced accumulation of lipid II sensitizes bacteria to antimicrobial fatty acids

A. E. Sidders, K. M. Kedziora, J. E. Beam, D. Bui, J. B. Parsons, S. E. Rowe, B. P. Conlon

This study shows that combining vancomycin with unsaturated fatty acids enhances killing of S. aureus by promoting lipid II accumulation and membrane disruption.

bioRxiv · May 3, 2022Microbiology

Inflammasome-mediated glucose limitation induces antibiotic tolerance in Staphylococcus aureus

J. E. Beam, N. J. Wagner, K.-Y. Lu, S. E. Rowe, B. P. Conlon

This study shows that S. aureus toxin activates the NLRP3 inflammasome in macrophages, leading to glucose limitation and antibiotic tolerance in the pathogen.

bioRxiv · Jan 22, 2022Microbiology

Macrophage-produced peroxynitrite induces antibiotic tolerance and supersedes intrinsic mechanisms of persister formation

J. E. Beam, N. J. Wagner, J. C. Shook, E. S. M. Bahnson, V. G. Fowler, S. E. Rowe, B. Conlon

This study shows that macrophage-produced peroxynitrite induces antibiotic tolerance in S. aureus, overriding intrinsic persister formation mechanisms observed in pure culture.

bioRxiv · May 20, 2021Microbiology