A. E. van der Meulen

This study maps CD4 T cell plasticity and spatial organization in IBD tissues, revealing regulatory-Th17 plasticity and interactions with CD8 cells.

The paper develops a 37-color spectral flow cytometry panel to analyze T cell phenotypes and cytokine expression in human intestinal samples, with applications in inflammatory bowel disease research.

The paper surveys Ruminococcus gnavus distribution across host lifestyles and health, revealing higher prevalence in Westernized populations and genomic differences between healthy and Crohn's disease isolates.