Continuous and bolus intraventricular topotecan prolong survival in a mouse model of leptomeningeal medulloblastoma
G. M. Shackleford, M. Mahdi, R. A. Moats, D. Hawes, H. C. Tran, T. Hoang, E. Meng, A. Erdreich-Epstein
This study compares continuous and bolus intraventricular topotecan in a mouse model of leptomeningeal medulloblastoma, finding both methods improve survival compared to systemic therapy.
bioRxiv · Oct 15, 2018Cancer Biology