Cancer BiologybioRxiv
Continuous and bolus intraventricular topotecan prolong survival in a mouse model of leptomeningeal medulloblastoma
G. M. Shackleford, M. Mahdi, R. A. Moats…·A. Erdreich-Epstein
This study compares continuous and bolus intraventricular topotecan in a mouse model of leptomeningeal medulloblastoma, finding both methods improve survival compared to systemic therapy.
DOI 10.1371/journal.pone.0206394