Large pan-cancer cell screen coupled to (phospho-) proteomics underscores high-dose vitamin C as a potent anti-cancer agent
A. Valles Marti, F. Böttger, E. Yau, K. Tejjani, L. Meijs, S. Sharma, M. Mumtaz, T. Le Large, A. Erozenci, D. Dekker, T. Schelfhorst, J. P. Medema, I. V. Bijnsdorp, J. C. Knol, S. R. Piersma, , C. R. Jimenez
This study evaluates high-dose vitamin C's anti-cancer effects across 51 cancer cell lines, finding high sensitivity and proteomic changes linked to cell cycle and immune pathways.
bioRxiv · Dec 19, 2023 · PreprintCancer Biology