Author

A. Felton

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Ecology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Research Focus:cell type annotation· 3 Organism:human· 3 Assay:CRISPR screen· 2 Approach:genetic perturbation / CRISPR· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

M. Emerman· 4 shared M. Ohainle· 3 shared A. Khalifeh· 1 shared A. M. Jensen· 1 shared E. M. Campbell· 1 shared H. Srinivasan· 1 shared J. Luban· 1 shared J. Twentyman· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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4 shared papersMicrobiology

M. Emerman

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

A CRISPR screen of HIV dependency factors reveals CCNT1 is non-essential in T cells but required for HIV-1 reactivation from latency

T. L. Hafer, A. Felton, Y. Delgado, H. Srinivasan, M. Emerman

This study uses a CRISPR screen to identify HIV-1 latency reversal factors, finding that CCNT1 is non-essential for T cell activation but critical for HIV reactivation from latency.

bioRxiv · Jul 28, 2023 · PreprintMicrobiology

Primate TRIM34 is a broadly-acting, TRIM5-dependent lentiviral restriction factor

J. Twentyman, A. Khalifeh, A. Felton, M. Emerman, M. Ohainle

This study identifies primate TRIM34 as a lentiviral restriction factor that requires TRIM5 for activity, restricting multiple SIV capsids across primate species.

bioRxiv · Mar 24, 2023Immunology

A Virus-Packageable CRISPR System Identifies Host Dependency Factors Across Multiple HIV-1 Strains

V. R. Montoya, T. M. Ready, A. Felton, S. R. Fine, M. OhAinle, M. Emerman

The paper identifies host dependency factors for HIV replication across multiple strains using a virus-packageable CRISPR system in human T cells.

bioRxiv · Nov 3, 2022 · PreprintMicrobiology

What happens to oak growth and survival when there is both competition and browsing?

A. M. Jensen, L. K. Petersson, A. Felton, M. Löf, M. A. M. Persson

This study quantifies the individual and combined effects of competition and browsing on oak growth and survival in temperate forests using a long-term field experiment.

bioRxiv · Mar 9, 2020 · PreprintEcology

TRIM34 acts with TRIM5 to restrict HIV and SIV capsids

M. Ohainle, K. Kim, S. Keceli, A. Felton, E. M. Campbell, J. Luban, M. Emerman

This study identifies TRIM34 as an HIV-1 capsid-targeting restriction factor that acts with TRIM5alpha to restrict HIV and SIV infection during reverse transcription.

bioRxiv · Oct 30, 2019 · PreprintMicrobiology