Chronic Staphylococcus aureus lung infection correlates with proteogenomic and metabolic adaptations leading to an increased intracellular persistence
X. TAN, M. Coureuil, E. Ramond, D. Euphrasie, M. Dupuis, F. Tros, J. Meyer, I. Nemanzny, C. Chhuon, I. C. Guerrera, A. Ferroni, I. Sermet-Gaudelus, X. Nassif, A. Charbit, A. Jamet
This study shows that S. aureus isolates from CF patients have increased intracellular persistence and metabolic adaptations, suggesting an intracellular niche contributes to chronic lung infection.
bioRxiv · Oct 16, 2018Microbiology