Author

A. Fraenkli

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

D. Hacker· 1 shared D. Ni· 1 shared F. Lehmann· 1 shared F. Pojer· 1 shared H. Stahlberg· 1 shared K. Lau· 1 shared

Activity by Year

2020-2020 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperBiophysics

D. Hacker

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1 paper

Recent·Most cited

Structural investigation of ACE2 dependent disassembly of the trimeric SARS-CoV-2 Spike glycoprotein

D. Ni, K. Lau, F. Lehmann, A. Fraenkli, D. Hacker, F. Pojer, H. Stahlberg

This study uses cryo-EM to show that hACE2 binding causes SARS-CoV-2 Spike trimer disassembly and S1 domain rearrangement, suggesting a mechanism for soluble hACE2's therapeutic effect.

bioRxiv · Oct 12, 2020 · PreprintBiophysics