Structures of the Cmr-βComplex Reveal the Regulation of the Immunity Mechanism of Type III-B CRISPR-Cas
N. Sofos, M. Feng, S. Stella, T. Pape, A. Fuglsgang, J. Lin, Q. Huang, Y. Li, Q. She, G. Montoya
This study reveals how target RNA binding regulates Cmr-β complex activities through conformational changes, enabling immune responses against genetic invaders.
bioRxiv · Jun 24, 2020Biochemistry