A novel role for the tumor suppressor gene ITF2 in lung tumorigenesis and chemotherapy response
O. Pernia, A. Sastre-Perona, C. Rodriguez-Antolin, A. Garcia-Guede, M. Palomares-Bralo, R. Rosas, D. Sanchez-Cabrero, C. Rodriguez, R. Martin-Arenas, V. Pulido, J. de Castro, P. Santisteban, O. Vera, I. Ibanez de Caceres
This study identifies ITF2 as a tumor suppressor involved in cisplatin resistance and chemotherapy response in epithelial tumors, with potential as a biomarker and therapeutic target.
bioRxiv · Jan 15, 2020Cancer Biology