Author

P. Santisteban

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:drug response / drug discovery· 2 Research Focus:differential expression· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Garcia-Guede· 1 shared A. Sastre-Perona· 1 shared B. Huang· 1 shared C. E. McCoach· 1 shared C. Fernandez-Mendez· 1 shared C. Gomez· 1 shared C. J. Kuo· 1 shared C. M. Blakely· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

A. Garcia-Guede

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A focal adhesion kinase-YAP signaling axis drives drug tolerant persister cells and residual disease in lung cancer

F. Haderk, C. Fernandez-Mendez, L. Cech, J. Yu, I. M. Meraz, V. Olivas, D. Barbosa Rabago, D. L. Kerr, C. Gomez, D. V. Allegakoen, J. Guan, K. N. Shah, K. A. Herrington, O. M. Gbenedio, S. Nanjo, , T. G. Bivona

This study identifies a FAK-YAP signaling axis that drives drug-tolerant persister cells and residual disease in lung cancer, showing that inhibiting this axis improves tumor response to targeted therapies.

bioRxiv · Oct 23, 2021Cancer Biology

A novel role for the tumor suppressor gene ITF2 in lung tumorigenesis and chemotherapy response

O. Pernia, A. Sastre-Perona, C. Rodriguez-Antolin, A. Garcia-Guede, M. Palomares-Bralo, R. Rosas, D. Sanchez-Cabrero, C. Rodriguez, R. Martin-Arenas, V. Pulido, J. de Castro, P. Santisteban, O. Vera, I. Ibanez de Caceres

This study identifies ITF2 as a tumor suppressor involved in cisplatin resistance and chemotherapy response in epithelial tumors, with potential as a biomarker and therapeutic target.

bioRxiv · Jan 15, 2020Cancer Biology

Impaired miRNA processing by DICER1 downregulation endows thyroid cancer with increased aggressiveness

J. Ramirez-Moya, L. Wert-Lamas, G. Riesco-Eizaguirre, P. Santisteban

This study shows that DICER1 downregulation by miR-146b-5p promotes thyroid cancer aggressiveness and identifies potential therapeutic strategies.

bioRxiv · Jul 21, 2018Cancer Biology