The structural basis for forkhead box family specificity revealed by the crystal structure of human FOXN1 in complex with DNA
J. A. Newman, H. Aitkenhead, A. Gavard, I. A. Rota, A. E. Handel, G. A. Hollander, O. Gileadi
This paper presents the crystal structure of human FOXN1 bound to DNA, revealing structural basis for its specificity and reduced affinity for methylated DNA.
bioRxiv · Sep 26, 2018Biochemistry