Author

A. Ghanbarpour

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

J. H. Davis· 1 shared R. T. Sauer· 1 shared S. E. Cohen· 1 shared T. A. Baker· 1 shared T. A. Bell· 1 shared X. Fei· 1 shared

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2022-2022 · peak 1/yr

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1 shared paperBiochemistry

J. H. Davis

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1 paper

Recent·Most cited

A closed translocation channel in the substrate-free AAA+ ClpXP protease diminishes rogue degradation

A. Ghanbarpour, S. E. Cohen, X. Fei, T. A. Bell, T. A. Baker, J. H. Davis, R. T. Sauer

The paper presents cryo-EM structures of E. coli ClpXP, showing that a closed axial channel in ClpX enhances degradation specificity by preventing non-specific substrate entry.

bioRxiv · Aug 27, 2022Biochemistry