Author

S. E. Cohen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Organism:non-human primate· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

A. Ghanbarpour· 1 shared H. Park· 1 shared J. H. Davis· 1 shared N. Boodighian· 1 shared R. T. Sauer· 1 shared T. A. Baker· 1 shared T. A. Bell· 1 shared X. Fei· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 16 mutual co-author links

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1 shared paperBiochemistry

A. Ghanbarpour

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2 papers

Recent·Most cited

Investigating the roles for essential genes in the regulation of the circadian clock in Synechococcus elongatus using CRISPR interference

N. Boodighian, H. Park, S. E. Cohen

This study uses CRISPR interference to investigate essential genes' roles in the circadian clock of Synechococcus elongatus, finding that reduced expression of two genes affects circadian period.

bioRxiv · Oct 10, 2022 · PreprintMicrobiology

A closed translocation channel in the substrate-free AAA+ ClpXP protease diminishes rogue degradation

A. Ghanbarpour, S. E. Cohen, X. Fei, T. A. Bell, T. A. Baker, J. H. Davis, R. T. Sauer

The paper presents cryo-EM structures of E. coli ClpXP, showing that a closed axial channel in ClpX enhances degradation specificity by preventing non-specific substrate entry.

bioRxiv · Aug 27, 2022Biochemistry