Author

A. Goncharov

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Evolutionary Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:ecology & biodiversity· 1

Frequent Co-Authors

A. Ozcan· 2 shared D. Di Carlo· 2 shared H.-A. Joung· 2 shared O. B. Garner· 2 shared A. N. Fedorov· 1 shared A. O' Kula· 1 shared B. Palanisamy· 1 shared C. Abergel· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersBioengineering

A. Ozcan

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Single-tier point-of-care serodiagnosis of Lyme disease

R. Ghosh, H.-A. Joung, A. Goncharov, B. Palanisamy, K. Ngo, K. Pejcinovic, N. Krockenberger, E. J. Horn, O. B. Garner, E. Ghazal, A. O' Kula, P. M. Arnaboldi, R. J. Dattwyler, A. Ozcan, D. Di Carlo

This paper develops a single-tier point-of-care serodiagnostic test for Lyme disease using synthetic peptides and machine learning, achieving sensitivity and specificity comparable to traditional two-tier lab tests.

bioRxiv · Jun 14, 2023 · PreprintBioengineering

Buffering role of HSP shapes the molecular evolution of mammalian and human genomes at short and long-term scales

V. N. Timonina, E. Tretiakov, A. Goncharov, K. Gunbin, J. Fellay, K. Popadin

This study shows that HSP90 buffering of slightly deleterious variants affects molecular evolution across species, tissues, and genes, with implications for predicting variant effects in the human genome.

bioRxiv · Nov 11, 2022 · PreprintEvolutionary Biology

High prevalence and diversity of beta-lactamase-encoding bacteria in cryosoils and ancient permafrost

S. Rigou, E. Christo-Foroux, S. Santini, A. Goncharov, J. Strauss, G. Grosse, A. N. Fedorov, K. Labadie, C. Abergel, J.-M. Claverie

This study identifies a high prevalence of beta-lactamase-encoding bacteria in Arctic and subarctic soils and permafrost, suggesting global warming could mobilize ancient DNA and contribute to antibiotic resistance.

bioRxiv · Mar 17, 2021Microbiology

DEEP LEARNING-ENABLED POINT-OF-CARE SENSING USING MULTIPLEXED PAPER-BASED SENSORS

Z. Ballard, H.-A. Joung, A. Goncharov, J. Liang, K. Nugroho, D. Di Carlo, O. B. Garner, A. Ozcan

This paper presents a deep learning framework for designing and quantifying point-of-care sensors, demonstrating a paper-based VFA for high-sensitivity hsCRP testing with competitive accuracy and hook-effect mitigation.

bioRxiv · Jun 11, 2019Bioengineering