Author

A. Granzhan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 3 Approach:experimental assay· 2 Research Focus:clustering· 1 Research Focus:drug response / drug discovery· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Gandolfini· 1 shared A. Joubert· 1 shared B. Heddi· 1 shared C. P. Gros· 1 shared D. Gomez· 1 shared D. Monchaud· 1 shared E. Defrancq· 1 shared F. Wojciechowski· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperBiophysics

A. Gandolfini

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3 papers

Recent·Most cited

iMab Antibody Binds Single-Stranded Cytosine-Rich Sequences and Unfolds DNA i-Motifs

J. Boissieras, H. Bonnet, M. F. Susanto, D. Gomez, A. Granzhan, E. Defrancq, J. Dejeu

This study investigates how iMab binds to cytosine-rich DNA sequences and unfolds i-Motifs, showing it binds to 2-3 cytosine blocks and unfolds iMs in acidic conditions.

bioRxiv · Nov 21, 2023Biophysics

Disclosing the actual efficiency of G-quadruplex DNA-disrupting small molecules

J. Mitteaux, P. Lejault, M. Pirrotta, F. Wojciechowski, A. Joubert, N. Desbois, C. P. Gros, R. H. E. Hudson, J.-B. Boule, A. Granzhan, D. Monchaud

The paper develops an in vitro assay to identify G4-disrupting molecules and characterizes a prototype small molecule that destabilizes G4-DNA.

bioRxiv · Nov 16, 2020Biophysics

Harnessing intrinsic fluorescence for typing of secondary structures of DNA

M. Zuffo, A. Gandolfini, B. Heddi, A. Granzhan

This paper uses intrinsic DNA fluorescence to classify secondary structures, showing successful clustering of oligonucleotides into conformational groups and assessing G4-forming propensity without labeling.

bioRxiv · Jan 15, 2020Biophysics