Author

P. Lejault

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:DNA methylation· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

D. Monchaud· 2 shared J.-P. Perreault· 2 shared M.-p. Terrier· 2 shared A. Granzhan· 1 shared A. Joubert· 1 shared A. Vannutelli· 1 shared C. Bernhard· 1 shared C. Brand· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersBiophysics

D. Monchaud

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

G-quadruplexe as a structural modulator of Intron Retention upon viral infection

P. Lejault, M.-p. Terrier, A. Vannutelli, C. Brand, M. Bisaillon, J.-P. Perreault

This study investigates the role of G-quadruplex structures in intron retention during Flavivirus infections, revealing their impact on alternative splicing and identifying a specific RNA-binding protein signature.

bioRxiv · Apr 12, 2023 · PreprintBiochemistry

Small molecule chaperones facilitate the folding of long-non coding RNA

P. Lejault, L. Prudent, M.-P. Terrier, J.-P. Perreault

The paper investigates how small molecule chaperones facilitate the folding of long non-coding RNA by stabilizing G-quadruplex structures.

bioRxiv · Apr 4, 2023 · PreprintBiophysics

Biomimetic, smart and multivalent ligands for G-quadruplex isolation and bioorthogonal imaging

F. Rota Sperti, T. Charbonnier, P. Lejault, J. Zell, C. Bernhard, I. E. Valverde, D. Monchaud

This paper introduces biomimetic, multivalent ligands (TASQs) for isolating and imaging G-quadruplexes in human cells using affinity capture and biotin/avidin pretargeted imaging.

bioRxiv · Dec 18, 2020Biophysics

Disclosing the actual efficiency of G-quadruplex DNA-disrupting small molecules

J. Mitteaux, P. Lejault, M. Pirrotta, F. Wojciechowski, A. Joubert, N. Desbois, C. P. Gros, R. H. E. Hudson, J.-B. Boule, A. Granzhan, D. Monchaud

The paper develops an in vitro assay to identify G4-disrupting molecules and characterizes a prototype small molecule that destabilizes G4-DNA.

bioRxiv · Nov 16, 2020Biophysics