BiophysicsbioRxiv
Disclosing the actual efficiency of G-quadruplex DNA-disrupting small molecules
J. Mitteaux, P. Lejault, M. Pirrotta…·D. Monchaud
The paper develops an in vitro assay to identify G4-disrupting molecules and characterizes a prototype small molecule that destabilizes G4-DNA.
DOI 10.1021/jacs.1c04426