Author

A. Hagelkruys

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

A. Mirazimi· 2 shared J. M. Penninger· 2 shared A. Bergthaler· 1 shared A. Hladik· 1 shared A. Ohradanova-Repic· 1 shared B. Agerer· 1 shared C. Oostenbrink· 1 shared F. Oberndorfer· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersMicrobiology

A. Mirazimi

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Low Density Lipoprotein Receptor-Related Protein 1 (LRP1) as an auxiliary host factor for RNA viruses including SARS-CoV-2

S. Devignot, T. W. Sha, T. R. Burkard, P. Schmerer, A. Hagelkruys, A. Mirazimi, U. Elling, J. M. Penninger, F. Weber

This study identifies LRP1 as a host factor that supports infection by multiple RNA viruses, including SARS-CoV-2, through cholesterol-dependent endocytosis.

bioRxiv · Feb 17, 2022 · PreprintMicrobiology

ACE2 is the critical in vivo receptor for SARS-CoV-2 in a novel COVID-19 mouse model with TNF- and IFNγ-driven immunopathology

R. Gawish, P. Starkl, L. Pimenov, A. Hladik, K. Lakovits, F. Oberndorfer, S. J. F. Cronin, A. Ohradanova-Repic, G. Wirnsberger, B. Agerer, L. Endler, T. Capraz, J. W. Perthold, A. Hagelkruys, N. Montserrat, , S. Knapp

This paper develops a mouse-adapted SARS-CoV-2 strain, maVie16, to model COVID-19 in mice, showing that ACE2 is critical for disease and that blocking TNF/IFNγ reduces immunopathology.

bioRxiv · Aug 9, 2021Immunology