Author

A. Hayat

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. B. Montgomery· 1 shared A. Doe· 1 shared A. Ors· 1 shared B. Bardestein-Wald· 1 shared D. Shitrit· 1 shared E. Carter· 1 shared G. Epstein-Shochet· 1 shared G. Ficz· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperPharmacology & Toxicology

A. B. Montgomery

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2 papers

Recent·Most cited

Low HER2 enables dedifferentiation and transformation of normal breast epithelial cells via chromatin opening

A. Hayat, E. Carter, H. W. King, A. Ors, A. Doe, S. A. Teijeiro, S. Charrot, S. Godinho, P. R. Cutillas, H. Mohammed, R. P. Grose, G. Ficz

This study shows that low HER2 levels enable dedifferentiation and transformation of breast epithelial cells through chromatin opening.

Disease Models & Mechanisms · Feb 1, 2023Peer-reviewedCancer Biology

Inhalation: A means to explore and optimize nintedanib's pharmacokinetic/pharmacodynamic relationship

G. Epstein-Shochet, S. Pham, S. Beck, S. Naiel, O. Mekhael, S. Revill, A. Hayat, M. Vierhout, B. Bardestein-Wald, D. Shitrit, K. Ask, A. B. Montgomery, M. Kolb, M. Surber

This paper investigates the pharmacokinetic/pharmacodynamic relationship of inhaled nintedanib for IPF treatment, showing that short-duration inhaled doses can achieve equivalent or superior efficacy compared to long-duration oral doses.

bioRxiv · Mar 27, 2020Pharmacology & Toxicology