Author

R. P. Grose

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:ATAC-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

E. Carter· 2 shared A. Cameron· 1 shared A. Doe· 1 shared A. Hayat· 1 shared A. Ors· 1 shared A. Samadi· 1 shared E. J. Tyler· 1 shared E. Murray· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersCancer Biology

E. Carter

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Author profile →

3 papers

Recent·Most cited

Low HER2 enables dedifferentiation and transformation of normal breast epithelial cells via chromatin opening

A. Hayat, E. Carter, H. W. King, A. Ors, A. Doe, S. A. Teijeiro, S. Charrot, S. Godinho, P. R. Cutillas, H. Mohammed, R. P. Grose, G. Ficz

This study shows that low HER2 levels enable dedifferentiation and transformation of breast epithelial cells through chromatin opening.

Disease Models & Mechanisms · Feb 1, 2023Peer-reviewedCancer Biology

Extracellular ATP drives pancreatic cancer cell invasion via purinergic receptor-integrin interactions

E. Tomas Bort, M. Joseph, Q. Wang, E. Carter, N. Roth, J. Gibson, A. Samadi, H. Kocher, S. Simoncelli, P. J. McCormick, R. P. Grose

This study identifies P2RY2 as a key purinergic receptor involved in pancreatic cancer invasion through interactions with integrins, suggesting therapeutic targeting potential.

bioRxiv · Oct 24, 2022Cancer Biology

Opposing roles for ADAMTS2 and ADAMTS14 in myofibroblast differentiation and function

E. P. Carter, K. K. Yoneten, N. Gavara, E. J. Tyler, V. Gauthier, E. Murray, A. Cameron, O. M. T. Pearce, R. P. Grose

The paper investigates the opposing roles of ADAMTS2 and ADAMTS14 in myofibroblast differentiation and function in pancreatic cancer stellate cells using 3D chimeric spheroids and bulk-RNA sequencing.

bioRxiv · Sep 20, 2022Cancer Biology