Author

P. R. Cutillas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:proteomics· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Doe· 1 shared A. Hayat· 1 shared A. Ors· 1 shared C. Vieitez· 1 shared D. Bradley· 1 shared E. Carter· 1 shared F. K. Mardakheh· 1 shared G. Ficz· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperCancer Biology

A. Doe

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Author profile →

3 papers

Recent·Most cited

Low HER2 enables dedifferentiation and transformation of normal breast epithelial cells via chromatin opening

A. Hayat, E. Carter, H. W. King, A. Ors, A. Doe, S. A. Teijeiro, S. Charrot, S. Godinho, P. R. Cutillas, H. Mohammed, R. P. Grose, G. Ficz

This study shows that low HER2 levels enable dedifferentiation and transformation of breast epithelial cells through chromatin opening.

Disease Models & Mechanisms · Feb 1, 2023Peer-reviewedCancer Biology

Targeted therapy for LIMD1-deficient non-small cell lung cancer subtypes.

K. Davidson, P. Grevitt, M. Contreras, K. S. Bridge, M. Hermida, K. M. Shah, F. K. Mardakheh, M. Stubbs, P. A. Clarke, R. Burke, P. Casado-Izquierdo, P. R. Cutillas, S. A. Martin, T. V. Sharp

This paper identifies PF-477736 as a selective cytotoxic compound for LIMD1-deficient NSCLC cells and xenograft models, offering a potential targeted therapy for this understudied cancer subtype.

bioRxiv · Feb 1, 2021Cancer Biology

Global analysis of specificity determinants in eukaryotic protein kinases

D. Bradley, C. Vieitez, V. Rajeeve, P. R. Cutillas, P. Beltrao

The paper identifies 30 putative specificity determinant residues in protein kinases and shows their conservation and mutation patterns in cancer and evolution.

bioRxiv · Aug 20, 2018Cell Biology