Resistance to the antifungal activity of Aprotinin occurs through mutations in genes that function in cation homeostasis
A. I. McColl, R. Lowe, J. Mckenna, M. Anderson, M. Bleackley
This study identifies mutations in ptk2 and sky1 genes as the cause of resistance to the antifungal activity of aprotinin in S. cerevisiae by disrupting magnesium homeostasis.
bioRxiv · Jun 22, 2020 · PreprintMicrobiology