M. Anderson

OPTIMIZATION OF DRIED BLOOD SPOT ASSAYS FOR HEPATITIS B VIRUS SURFACE ANTIBODY QUANTIFICATION

The paper optimizes a dried blood spot (DBS) elution protocol for hepatitis B surface antibody (anti-HBs) quantification, finding that 450 or 500uL PBS and 3hr agitation yield results comparable to plasma, with 25°C storage being optimal.

Transcriptional control of central T cell tolerance by NR4A family nuclear receptors

This study identifies the role of Nr4a family nuclear receptors in transcriptional control of T cell tolerance during thymic development, showing their necessity for negative selection and anergy-like programs in self-reactive T cells.

Assessment of the Histone Mark-based Epigenomic Landscape in Human Myometrium at Term Pregnancy

This study maps the epigenomic landscape of human myometrium at term pregnancy, identifying enhancers and regulatory elements associated with PGR and PLCL2.

Silver nanoparticles can be sampled by ultrafiltration probe but elution into & recovery from plasma and DPBS differs in vitro

This study compares AgNP elution and recovery in DPBS and plasma using UF probes and pipette sampling, finding differences in elution patterns and recovery efficiency.

Glucocorticoids suppress NF-κB-mediated neutrophil control of Aspergillus fumigatus hyphal growth

This study shows glucocorticoids increase susceptibility to Aspergillus fumigatus infection by suppressing NF-κB-mediated neutrophil control of hyphal growth in zebrafish larvae.

PURA and GLUT1: Sweet partners for brain health

This study investigates the interaction between PURA and GLUT1, showing PURA regulates glucose uptake via GLUT1 function without affecting its expression.

Adipose-derived exosomal miR-421 targets CBX7 and promotes metastatic potential in ovarian cancer cells

This study identifies adipose-derived exosomal miR-421 as a regulator of CBX7 expression, promoting ovarian cancer metastasis by inducing epigenetic changes.

Shared and Distinct Mechanisms of UBA1 Inactivation Across Different Diseases

This study identifies shared and distinct mechanisms of UBA1 inactivation in VEXAS syndrome and related diseases, revealing how different mutations affect ubiquitin transfer to E2 enzymes.

Gardnerella Diversity and Ecology in Pregnancy and Preterm Birth

This study examines Gardnerella diversity in vaginal microbiomes across populations and its association with preterm birth, revealing intra-species variation and its impact on microbial composition.

De novo identification of CD4+ T cell epitopes

This study develops a method combining experimental and computational approaches to identify CD4+ T cell epitopes using SABR-II libraries and single-cell RNA sequencing.

Structural Premise of Selective Deubiquitinase USP30 Inhibition by Small-Molecule Benzosulfonamides

This study investigates how a benzosulfonamide compound inhibits USP30, a mitochondrial deubiquitylating enzyme, using biochemical and structural methods to reveal its binding mechanism and selectivity.

Structural basis for acyl chain control over glycosphingolipid sorting and vesicular trafficking

The paper identifies a structural motif in ceramide acyl chains that determines glycosphingolipid sorting via endocytic pathways and shows its dependence on cholesterol.

CRISPR/Cas-9 mediated knock-in by homology dependent repair in the West Nile Virus vector Culex quinquefasciatus Say

This paper demonstrates the first successful germline gene knock-in in Culex quinquefasciatus using CRISPR/Cas9 and homology-dependent repair, achieving a 2.8% transformation rate with a recessive lethal phenotype.

Resistance to the antifungal activity of Aprotinin occurs through mutations in genes that function in cation homeostasis

This study identifies mutations in ptk2 and sky1 genes as the cause of resistance to the antifungal activity of aprotinin in S. cerevisiae by disrupting magnesium homeostasis.

Evaluation of Reproducible and Transparent Research Practices in Sports Medicine Research: A Cross-sectional study

This study evaluates reproducibility and transparency in sports medicine research by analyzing 195 publications and finds that most lack data availability statements, protocols, analysis scripts, or pre-registration.

Functional diversification enabled grassy biomes to fill global climate space

The paper maps global grassy biomes and identifies key traits and lineages driving their distribution across climates.

Candida albicans dispersed cells signify a developmental state distinct from biofilm and planktonic phases

The paper identifies dispersed Candida albicans cells as a distinct developmental state with unique transcriptomic features compared to biofilm and planktonic phases.