A high throughput bispecific antibody discovery pipeline
A. I. Segaliny, J. Jayaraman, X. Chen, J. Chong, R. Luxon, A. Fung, Q. Fu, X. Jiang, R. Rivera, X. Ma, C. Ren, J. Zimak, P. N. Hedde, Y. Shang, G. Wu, W. Zhao
This paper introduces a high throughput single-cell pipeline for bispecific antibody discovery, demonstrating its efficiency in identifying rare functional clones and uncovering design principles for improved immunotherapeutics.
bioRxiv · Sep 7, 2021Bioengineering