Author

A. Igel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:protein folding & dynamics· 2 Assay:protein structure· 2 Organism:rat· 2 Research Focus:cell type annotation· 1

Frequent Co-Authors

F. Reine· 2 shared H. Klute· 2 shared H. Rezaei· 2 shared L. Herzog· 2 shared V. Beringue· 2 shared D. Martin· 1 shared F. Halgand· 1 shared F. Sailer· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersBiochemistry

F. Reine

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

The smallest infectious substructure encoding the prion strain structural determinant revealed by spontaneous dissociation of misfolded prion protein assemblies

J. Bohl, M. Moudjou, L. Herzog, F. Reine, F. Sailer, H. Klute, F. Halgand, G. Vand der Rest, Y. Boulard, A. Igel, V. Beringue, H. Rezaei

The paper identifies small infectious prion oligomers that encode the strain structural determinant, showing prion infectivity and SSD are not exclusive to amyloid fibrils.

bioRxiv · Mar 21, 2023Biochemistry

Pathogenicity, strain properties and interspecies transmission capacity of pure recombinant prion protein assemblies

H. Rezaei, D. Martin, L. Herzog, F. Reine, N. Aron, A. Igel, H. Klute, S. Youssafi, J.-B. Moog, P. Sibille, O. Andreoletti, J. Torrent, V. Beringue

This paper generates prions from recombinant prion protein assemblies with distinct biological properties and shows their transmissibility to mice, revealing structural features critical for prion pathobiology.

bioRxiv · Feb 27, 2023 · PreprintMicrobiology