Tobramycin adaptation alters the antibiotic susceptibility of Pseudomonas aeruginosa quorum sensing-null mutants
R. G. Abisado-Duquea, B. M. McKee, K. A. Townsend, K. Woods, P. Koirala, A. J. Holder, V. D. Craddock, M. T. Cabeen, J. R. Chandler
This study shows that a mutation in fusA1 enhances tobramycin resistance in lasR-null Pseudomonas aeruginosa mutants through interactions with the MexXY efflux pump and ArmZ regulator.
bioRxiv · Jan 13, 2023 · PreprintMicrobiology