Author

A. J. Keung

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 4 Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Organism:human· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Research Focus:cell signaling & trafficking· 2 Assay:organoid / primary culture· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

A. Voulgaropoulos· 2 shared D. Sen· 2 shared T. Rudibaugh· 2 shared A. G. Hass· 1 shared A. Simpson· 1 shared B. M. Rao· 1 shared E. W. Indermaur· 1 shared J. N. Meanor· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersBioengineering

A. Voulgaropoulos

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Author profile →

6 papers

Recent·Most cited

Reactive Oxygen Species Mediate Transcriptional Responses to Dopamine and Cocaine in Human Cerebral Organoids

T. Rudibaugh, A. J. Keung

This study investigates how dopamine and cocaine affect human cerebral organoids, revealing ROS-mediated transcriptional responses and novel pathways in ventral forebrain development.

bioRxiv · Jun 13, 2023Cell Biology

Single cell assessment of human stem cell derived mesolimbic models and their responses to substances of abuse.

T. Rudibaugh, R. Tam, R. C. Estridge, A. J. Keung

This study characterizes human stem cell-derived mesolimbic models and their transcriptomic responses to dopamine, cocaine, and morphine.

bioRxiv · May 12, 2023Cell Biology

Identifying challenges and opportunities for histone peptides in protein engineering platforms

J. N. Meanor, A. J. Keung, B. M. Rao

This study identifies challenges in using histone peptides in protein engineering platforms and shows that manipulating binding avidity can improve specificity.

bioRxiv · Dec 28, 2021 · PreprintBioengineering

Effects of early geometric confinement on the transcriptomic profile of human cerebral organoids

D. Sen, A. Voulgaropoulos, A. J. Keung

This study examines how early geometric confinement affects the transcriptomic profile of human cerebral organoids, finding shape-dependent effects on neural lineage specification.

bioRxiv · Feb 18, 2021 · PreprintBioengineering

Human cerebral organoids capture the spatiotemporal complexity and disease dynamics of UBE3A

D. Sen, A. Voulgaropoulos, Z. Drobna, A. J. Keung

This study shows human cerebral organoids can model UBE3A expression dynamics and disease responses in Angelman Syndrome and Autism Spectrum Disorder.

bioRxiv · Aug 22, 2019Bioengineering

Driving the scalability of DNA-based information storage systems

K. J. Tomek, K. Volkel, A. Simpson, A. G. Hass, E. W. Indermaur, J. Tuck, A. J. Keung

This paper develops a nested file address system for DNA storage, increasing theoretical capacity by five orders of magnitude and enabling practical DNA-based data storage systems.

bioRxiv · Apr 13, 2019Bioengineering