Author

A. J. Lopez

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 2 Animal Behavior & Cognition· 1 Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 5 Research Focus:cell type annotation· 2 Organism:mouse· 2 Assay:behavioral assay· 1 Assay:cryo-EM· 1 Organism:plant (other)· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

I. Kursula· 3 shared J. Vahokoski· 2 shared L. J. Calder· 2 shared P. B. Rosenthal· 2 shared A. Freitag· 1 shared A. La Torre· 1 shared A. Moshiri· 1 shared A. R. Johnson· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersBiochemistry

I. Kursula

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Structure and function of Plasmodium actin II in the parasite mosquito stages

A. J. Lopez, M. Andreadaki, J. Vahokoski, E. Deligianni, L. J. Calder, S. Camerini, A. Freitag, U. Bergmann, P. B. Rosenthal, I. Siden-Kiamos, I. Kursula

This study characterizes Plasmodium actin II, showing it forms stable filaments, associates with the nucleus in gametocytes and zygotes, and requires methylation of histidine 73 for function.

bioRxiv · Nov 22, 2022 · PreprintBiochemistry

Retinal organoids derived from rhesus macaque iPSCs undergo accelerated differentiation compared to human stem cells

A. J. Lopez, S. Kim, X. Qian, J. Rogers, J. T. Stout, S. M. Thomasy, A. La Torre, R. Chen, A. Moshiri

This study compares retinal organoid differentiation speed between rhesus macaque and human stem cells, finding NHP-derived organoids develop faster.

bioRxiv · May 25, 2021Cell Biology

High-resolution structures of malaria parasite actomyosin and actin filaments

J. Vahokoski, L. J. Calder, A. J. Lopez, J. E. Molloy, P. B. Rosenthal, I. Kursula

This paper presents the first high-resolution structure of the malaria parasite actomyosin motor complex and reveals new atomic details of the ATPase site and conformational changes.

bioRxiv · Jul 2, 2020Biophysics

A novel multidimensional reinforcement task in mice elucidates sex-specific behavioral strategies

M. G. Kutlu, J. E. Zachry, L. J. Brady, P. R. Melugin, C. Sanders, J. Tat, A. R. Johnson, K. Thibeault, A. J. Lopez, E. S. Calipari

This study introduces a multidimensional reinforcement task in mice to assess sex-specific behavioral strategies, finding females prioritize avoidance over reward seeking while males prioritize reward seeking.

bioRxiv · Jul 2, 2019Animal Behavior & Cognition

Atomic view into Plasmodium actin polymerization, ATP hydrolysis, and phosphate release

E.-P. Kumpula, A. J. Lopez, L. Tajedin, H. Han, I. Kursula

The paper investigates the structural mechanisms of Plasmodium actin polymerization, ATP hydrolysis, and phosphate release using crystallography, revealing how the A-loop regulates filament stability.

bioRxiv · Nov 9, 2018Biochemistry