Author

A. J. Silver

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

A. E. Gorska· 1 shared D. J. Brown· 1 shared H. E. Ramsey· 1 shared J. M. Watke· 1 shared L. Tanner· 1 shared M. R. Savona· 1 shared S. D. Olmstead· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

A. E. Gorska

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1 paper

Recent·Most cited

Repair of leukemia-associated single nucleotide variants via interallelic gene conversion

A. J. Silver, D. J. Brown, S. D. Olmstead, J. M. Watke, A. E. Gorska, L. Tanner, H. E. Ramsey, M. R. Savona

This study demonstrates that CRISPR-mediated interallelic gene conversion can revert heterozygous SNVs in leukemia cells without exogenous templates, improving survival in xenograft models.

bioRxiv · Apr 16, 2024 · PreprintCancer Biology