Author

A. Jekabsone

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

A. A. Genazzani· 1 shared A. Ariotti· 1 shared A. Tunaityte· 1 shared A. Volkeviciute· 1 shared C. Casali· 1 shared C. Distasi· 1 shared C. Matute· 1 shared D. Gecys· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCell Biology

A. A. Genazzani

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2 papers

Recent·Most cited

ER-mitochondria distance is a critical parameter for efficient mitochondrial Ca2+ uptake and oxidative metabolism.

G. Dematteis, L. Tapella, C. Casali, M. Talmon, E. Tonelli, S. Reano, A. Ariotti, E. Pessolano, M. Malecka, G. Chrostek, G. Kilkoviene, D. Umbrasas, C. Distasi, M. Grilli, G. Ladds, , D. Lim

The paper shows that an optimal ER-mitochondria distance of ~20 nm is critical for efficient Ca2+ transfer and mitochondrial oxidative metabolism, with reduced distances observed in Parkinson's disease astrocytes.

bioRxiv · Jul 24, 2024Cell Biology

Comparison of mitochondrial response to SARS-CoV-2 spike protein receptor binding domain in human lung microvascular, coronary artery endothelial and bronchial epithelial cells

G. Kulkoviene, D. Narauskaite, A. Tunaityte, A. Volkeviciute, Z. Balion, O. Kutakh, D. Gecys, M. Kairyte, M. Uldukyte, E. Stankevicius, A. Jekabsone

The paper examines how SARS-CoV-2 spike protein RBD affects mitochondrial function and inflammation in three human cell types, finding increased mitoROS and cytokine expression in all, with HLMVEC showing the strongest response.

bioRxiv · Dec 19, 2023 · PreprintImmunology