Next generation vaccine platform: polymersomes as stable nanocarriers for a highly immunogenic and durable SARS-CoV-2 spike protein subunit vaccine
J. H. Lam, A. K. Khan, T. A. Cornell, R. J. Dress, T. W. Chia, W. W. W. Yeow, N. K. Mohd-Ismail, S. Venkatraman, K. T. Ng, Y.-J. Tan, D. E. Anderson, F. Ginhoux, M. Nallani
This paper develops a subunit vaccine using polymersomes to deliver SARS-CoV-2 spike protein and CpG adjuvant, showing robust and durable immune responses in mice.
bioRxiv · Jan 24, 2021 · PreprintImmunology